Endocrine Abstracts

The pituitary adenylate cyclase-activating polypeptide (PACAP), isolated for the first time from hypothalamic extracts (Miyata et al. 1989), was localized in some peripheral tissues such as adrenal, gastrointestinal tract, ovary and testis (Arimura et al. 1991, Watanabe et al. 1992, Gathei et al. 1993, Shioda et al. 1994, Kononen et al. 1994). It was previously demonstrated that in the testis PACAP was involved in the steroidogenesis r...